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Invitrogen™ HK2 Polyclonal Antibody
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Catalog No. PIPA5102329
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100 μL
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PIPA5102329 100 μL
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Catalog No. PIPA5102329 Supplier Invitrogen™ Supplier No. PA5102329
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Hexokinase II.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HK2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Hk2
Gene Accession No. O08528, P27881, P52789
Gene Alias AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
Gene Symbols Hk2
Host Species Rabbit
Immunogen A synthesized peptide derived from human HK2(Accession P52789), corresponding to amino acid residues P884-R917.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15277, 25059, 3099
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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