Invitrogen™ HKR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536148

Catalog No. PIPA536148

Description

This antibody detects endogenous protein at a molecular weight of 73 kDa. Purity is >95% by SDS-PAGE.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppeltype DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.

Specifications

• Antigen: HKR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HKR1
• Gene Alias: GLI-Kruppel family member HKR1; HKR1; HKR1, GLI-Kruppel zinc finger family member; Krueppel-related zinc finger protein 1; oncogene HKR1; Protein HKR1; Zinc finger protein 875; ZNF875
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 284459
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P10072
• Gene Symbols: HKR1
• Immunogen: Synthetic peptide corresponding to amino acids 111-160 of human HKR1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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