HLA-A25/HLA-Aw32 Mouse anti-Human, Clone: CATA-1, Abnova™

Mouse Monoclonal Antibody

Manufacturer:  Abnova Corporation MAB14280

Catalog No. 89-034-362

Description

Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.

• High specificity
• High reactivity

Specifications

• Antigen: HLA-A25/HLA-Aw32
• Clone: CATA-1
• Description: Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32.
• Formulation: In 10 mM PBS.
• Format: Liquid
• Gene Symbols: HLA-A
• Immunogen: Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10.
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3105|3106|3107
• Target Species: Human

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Accession No.: P01889;P30443;P30499
• Gene Alias: HLAA
• Host Species: Mouse
• Isotype: IgG2a, kappa
• Quantity: 100 ug
• Storage Requirements: Store at -20 to -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Monoclonal
• Test Specificity: This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.

For Research Use Only (RUO)