Invitrogen™ HLA-ABCE Monoclonal Antibody (TP25.99SF), Alexa Fluor™ 488

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544136

Catalog No. PIMA544136

Description

This antibody recognizes an extracellular epitope on HLA-ABC and HLA-E molecules, but not HLA-G. It can be used for discrimination between HLA-G and other HLA-class I antigens.

HLA-A, -B, and -C are major histocompatibility complex (MHC)-class I antigens. Like other class I molecules (i.e. HLA-E, -F, -G), HLA-A, -B, and -C are heterodimers consisting of a 40 - 45 kDa transmembrane glycoproteic alpha-chain, noncovalently combined to the invariant B2-microglobulin. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-ABCE
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide
• Gene Accession No.: P01889, P04439, P10321, P13747
• Gene Symbols: HLA-A, HLA-B, HLA-C, HLA-E
• Immunogen: IFN-gamma-treated human melanoma cells Colo 38.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: TP25.99SF
• Conjugate: Alexa Fluor 488
• Gene: HLA-E
• Gene Alias: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Host Species: Mouse
• Purification Method: Size-exclusion chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3105, 3106, 3107, 3133
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov