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Invitrogen™ HLA-DP Recombinant Rabbit Monoclonal Antibody (PD00-70)
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Catalog No. FEMA550758
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100 μL
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FEMA550758 100 μL
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Catalog No. FEMA550758 Supplier Invitrogen™ Supplier No. MA550758
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Human tonsil tissue, human diffuse large B-cell lymphoma tissue, Daudi. Predicted band size: 29 kDa Subcellular Location: Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane.

The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and -DP, all are highly polymorphic. HLA-DP molecules have not been studied extensively. HLA-DP is a protein complex found on the surface of antigen-presenting cells, such as dendritic cells, macrophages, and B cells. Its main function is to present peptides derived from extracellular proteins to CD4+ T cells for immune recognition. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DP
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone PD00-70
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene HLA-DPB1
Gene Accession No. P04440
Gene Alias beta1 domain MHC class II HLA DPB; class II HLA beta chain; DPB1; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA DP14-beta chain; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II HLA-DP-beta-1; MHC class II HLA-DRB1; MHC HLA DPB1
Gene Symbols HLA-DPB1
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3115
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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