HLA-DPA1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 161091AP
DescriptionHLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|DP(W3), DP(W4), HLA DP1A, HLA DPA1, HLA SB alpha chain, HLADP, HLADPA1, HLA-DPA1, HLASB, MHC class II DP3 alpha, MHC class II DPA1|
|HLA-DPA1 Fusion Protein Ag9031|
|Antigen Affinity Chromatography|
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