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HLA-DPB1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985903
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Catalog No. Quantity
50-198-5903 100 μL
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Catalog No. 50-198-5903 Supplier Bioss Supplier No. BS4107R
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Description

Rabbit Polyclonal Antibody

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Specifications

Antigen HLA-DPB1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene HLA-DPB1
Gene Accession No. P04440
Gene Alias beta1 domain MHC class II HLA DPB; class II HLA beta chain; DPB1; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA DP14-beta chain; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; MHC cla; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II HLA-DP-beta-1; MHC class II HLA-DRB1; MHC HLA DPB1
Gene Symbols HLA-DPB1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DPB1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3115
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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