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HLA-DPB1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 112981AP150UL

Encompass_Preferred

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Catalog No. 50-172-7039


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Description

Description

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Specifications

Specifications

HLA-DPB1
Polyclonal
Unconjugated
HLA-DPB1
DPB1, HLA DP1B, HLA DPB1, HLA-DPB1, MHC class II antigen DPB1
Rabbit
Antigen Affinity Chromatography
RUO
3115
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P04440
HLA-DPB1
HLA-DPB1 Fusion Protein Ag1815
150 μL
Primary
Human
Antibody
IgG
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