HLA DQ/DR/DP Antibody (HLA-Pan/2967R), Janelia Fluor™ 549, Novus Biologicals™

Catalog No.	Quantity
NB010904	0.1 mL

Catalog No. NB010904 Supplier Novus Biologicals Supplier No. NBP279843JF549

Description

Rabbit Monoclonal Antibody

HLA DQ/DR/DP Monoclonal specifically detects HLA DQ/DR/DP in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: HLA DQ/DR/DP
• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: HLA-Pan/2967R
• Conjugate: Janelia Fluor 549
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Alias: CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
• Gene Symbols: HLA-DQA1
• Host Species: Rabbit
• Immunogen: Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
• Purification Method: Protein A or G purified
• Quantity: 0.1 mL
• Regulatory Status: RUO
• Research Discipline: Adaptive Immunity, Asthma, Diabetes Research, Immunology
• Primary or Secondary: Primary
• Test Specificity: Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed ofan alpha chain(36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
• Target Species: Human
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG