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Invitrogen™ HLA-DQA1/DQA2 Polyclonal Antibody
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Catalog No. PIPA519388
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100 μg
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PIPA519388 100 μg
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Catalog No. PIPA519388 Supplier Invitrogen™ Supplier No. PA519388
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DQA1/DQA2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene HLA-DQA2
Gene Accession No. P01906, P01909
Gene Alias CD; CELIAC1; DC-1 alpha chain; DC-alpha; DQ alpha 2; DQ-A1; DX alpha chain; DX-ALPHA; GSE; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA class II histocompatibility antigen, DQ(W3) alpha chain; HLA-DCA; HLA-DQA; HLA-DQA1; HLA-DQA2; HLA-DXA; leucocyte antigen DQA1; leukocyte antigen alpha chain; major histocompatibility complex, class II, DQ alpha 1; major histocompatibility complex, class II, DQ alpha 2; MHC class II antigen; MHC class II DQA1; MHC class II DQA2; MHC class II HLA-D alpha glycoprotein; MHC class II HLA-DQ-alpha-1; MHC class II surface glycoprotein; MHC HLA-DQ alpha
Gene Symbols HLA-DQA1, HLA-DQA2
Host Species Goat
Immunogen Synthetic peptide sequence (QGLRSVGASRH) corresponding to the C-terminus amino acids of HLA-DQA2 (aa 241-251).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3117, 3118
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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