Invitrogen™ HLA-DQA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578002

Catalog No. PIPA578002

Description

Positive Control: A375 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HLA-DQA2 belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-DQA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HLA-DQA2
• Gene Alias: DQ alpha 2; DX ALPHA; DX alpha chain; DX-ALPHA; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA DXA; HLA-DQA1; HLA-DQA2; HLA-DXA; major histocompatibility complex, class II, DQ alpha 2; MHC class II DQA2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3118
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P01906
• Gene Symbols: HLA-DQA2
• Immunogen: Synthetic peptide encompassing a sequence within the Extracellular domain of human HLA-DQA2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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