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Invitrogen™ HLA-DQA2 Polyclonal Antibody
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Catalog No. PIPA597242
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100 μL
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PIPA597242 100 μL
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Catalog No. PIPA597242 Supplier Invitrogen™ Supplier No. PA597242
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EDIVADHVAS YGVNFYQSHG PSGQYTHEFD GDEEFYVDLE TKETVWQLPM FSKFISFDPQ SALRNMAVGK HTLEFMMRQS NSTAATNEVP EVTVFSKFPV TL; Positive Samples: Mouse liver, Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Endoplasmic reticulum membrane, Endosome membrane, Golgi apparatus, Lysosome membrane, Single-pass type I membrane protein, trans-Golgi network membrane.

HLA-DQA2 belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DQA2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Alias DQ alpha 2; DX ALPHA; DX alpha chain; DX-ALPHA; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA DXA; HLA-DQA1; HLA-DQA2; HLA-DXA; major histocompatibility complex, class II, DQ alpha 2; MHC class II DQA2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-125 of human HLA-DQA2 (NP_0644401).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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