Invitrogen™ HLA-F Monoclonal Antibody (3F11F4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548491

Catalog No. FERMA548491

Description

HLA-F Monoclonal Antibody for Western Blot, ICC/IF, IHC, Flow, ELISA

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-F
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P30511
• Gene Symbols: HLA-F
• Immunogen: Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: 3F11F4
• Conjugate: Unconjugated
• Gene: HLA-F
• Gene Alias: CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3134
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid