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Invitrogen™ HLA-F Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA543345
Description
Peptide sequence: PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN Sequence homology: Human: 100%; Pig: 100%.
HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Specifications
HLA-F | |
Polyclonal | |
Unconjugated | |
HLA-F | |
CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen | |
Rabbit | |
Affinity Chromatography | |
RUO | |
3134 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
P30511 | |
HLA-F | |
Synthetic peptide directed towards the N-terminal of human HLA-F (aa 71-120). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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