Invitrogen™ HLA-F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543345

Catalog No. PIPA543345

Description

Peptide sequence: PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN Sequence homology: Human: 100%; Pig: 100%.

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HLA-F
• Gene Alias: CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3134
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P30511
• Gene Symbols: HLA-F
• Immunogen: Synthetic peptide directed towards the N-terminal of human HLA-F (aa 71-120).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG