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Invitrogen™ HLA-F Polyclonal Antibody
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Catalog No. PIPA587858
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100 μL
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PIPA587858 100 μL
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Catalog No. PIPA587858 Supplier Invitrogen™ Supplier No. PA587858
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSHSLRYFST AVSRPGRGEP RYIAVEYVDD TQFLRFDSDA AIPRMEPREP WVEQEGPQYW EWTTGYAKAN AQTDRVALRN LLRRYNQSEA GSHTLQGMNG CDMGPDGRLL RGYHQHAYDG KDYISLNEDL RSWTAADTVA QITQRFYEAE EYAEEFRTYL EGECLELLR; Positive Samples: A-549; Cellular Location: Membrane, Single-pass type I membrane protein.

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-F
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.93 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HLA-F
Gene Accession No. P30511
Gene Alias CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen
Gene Symbols HLA-F
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-190 of human HLA-F (NP_0010919491).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3134
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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