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Invitrogen™ HLCS Polyclonal Antibody
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Catalog No. PIPA529050
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100 μL
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PIPA529050 100 μL
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Catalog No. PIPA529050 Supplier Invitrogen™ Supplier No. PA529050
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Rabbit Polyclonal Antibody

Recommended positive controls: K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLCS
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene HLCS
Gene Accession No. P50747
Gene Alias 410I21.SP6; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; Biotin apo-protein ligase; biotin--[acetyl-CoA-carboxylase] ligase; Biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Biotin--protein ligase; D16Jhu34; HCS; Hlcs; Holocarboxylase synthetase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase); RGD1565360
Gene Symbols HLCS
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human HCS. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3141
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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