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Invitrogen™ HLCS Polyclonal Antibody
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Catalog No. PIPA553599
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100 μL
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PIPA553599 100 μL
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Catalog No. PIPA553599 Supplier Invitrogen™ Supplier No. PA553599
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DLPYDYSSSL ESVADETSPE REGRRVNLTG KAPNILLYVG SDSQEALGRF HEVRSVLADC VDIDSYILYH LLEDSALRDP WTDNCLLLVI ATRESIPEDL YQKFMAYLSQ GGKVLGLSSS FTFGGFQV Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 73%.

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HLCS
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HLCS
Gene Accession No. P50747
Gene Alias 410I21.SP6; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; Biotin apo-protein ligase; biotin--[acetyl-CoA-carboxylase] ligase; Biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Biotin--protein ligase; D16Jhu34; HCS; Hlcs; Holocarboxylase synthetase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase); RGD1565360
Gene Symbols HLCS
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HLCS. Recombinant protein control fragment (Product #RP-91775).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3141
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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