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Tocris Bioscience™ HLI 373
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Catalog No. 350310
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35-031-0 10 mg
35-035-0 50 mg
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Catalog No. 35-031-0 Supplier Tocris Bioscience™ Supplier No. 3503/10
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Description

Hdm2 inhibitor; activates p53-dependent transcription

Inhibitor of Hdm2 ubiquitin ligase (E3). Blocks Hdm2-mediated ubiquitylation and proteasomal degradation of p53; activates p53-dependent transcription. Induces apoptosis in several tumor cell lines that express wild-type p53 such as LOX-IMVI, A549, HT1080 and U2OS.

Chemical Identifiers

CAS 1782531-99-0

Specifications

Quantity 10 mg
Molecular Formula C18H25Cl2N5O2
Formula Weight 414.33
Purity >99%
Molecular Weight (g/mol) 414.33
Chemical Name or Material HLI 373

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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