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Invitrogen™ HM13 Polyclonal Antibody
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Catalog No. PIPA569652
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100 μL
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PIPA569652 100 μL
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Catalog No. PIPA569652 Supplier Invitrogen™ Supplier No. PA569652
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 92%.

Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection. May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1. Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139- dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HM13
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene H13
Gene Accession No. Q9D8V0
Gene Alias 1200006O09Rik; 4930443L17Rik; 5031424B04Rik; AV020344; cb228; H13; H-13; hIMP1; histocompatibility (minor) 13; histocompatibility 13; histocompatibility minor 13; HM13; hm13 protein; IMP1; IMP-1; IMPAS; IMPAS-1; intramembrane aspartyl protease; intramembrane protease 1; minor histocompatibility antigen 13; minor histocompatibility antigen H13; MSTP086; presenilin-like aspartyl protease; presenilin-like protein 3; PSENL3; PSL3; Signal peptide peptidase; signal peptide peptidase beta; signal peptide peptidase like 1; SPP; SPPL1; Unknown (protein for MGC:134054); wu:fc11a06; zgc:56660; zgc:86862
Gene Symbols H13
Host Species Rabbit
Immunogen synthetic peptide corresponding to a region of mouse HM13 (aa 240-289).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14950
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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