Invitrogen™ HMGA1 Recombinant Rabbit Monoclonal Antibody (5J0E6)

Catalog No.	Quantity
PIMA535485	100 μL

Catalog No. PIMA535485 Supplier Invitrogen™ Supplier No. MA535485

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPVSPGTA LVGSQKEPSE VPTPKRPRGR PKGSKNKGAA KTRKTTTTPG RKPRGRPKKL EKEEEEGISQ ESSEEEQ.

HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

Specifications

• Antigen: HMGA1
• Applications: ChIP sequencing (ChIP-seq), ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 5J0E6
• Concentration: 1.6 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: HMGA1
• Gene Accession No.: P17095, P17096, Q8K585
• Gene Alias: AL023995; HGNC:5010; high mobility group AT-hook 1; high mobility group AT-hook protein 1; high mobility group HMGA1A; high mobility group HMGA1B; high mobility group protein; high mobility group protein 1A; high mobility group protein A1; high mobility group protein A1A; high mobility group protein A1B; high mobility group protein HMG-I/HMG-Y; high mobility group protein I; high mobility group protein R; high mobiliy group protein A1B; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1; Hmga1a; Hmga1b; Hmgi; HMG-I(Y); HMGIY; HMG-R; Hmgy; MGC12816; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; non-histone protein; non-histone protein; HMGA1A; non-histone protein; HMGA1B; OTTHUMP00000016222; OTTHUMP00000016223; OTTHUMP00000016224; OTTHUMP00000039618
• Gene Symbols: HMGA1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-107 of human HMGA1 (P17096).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117062, 15361, 3159
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG