Invitrogen™ HMGA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578008

Catalog No. PIPA578008

Description

Positive Control: 293T, H1299, HCT116 Predicted Reactivity: Mouse (100%), Rat (100%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

Specifications

• Antigen: HMGA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMGA1
• Gene Alias: AL023995; HGNC:5010; high mobility group AT-hook 1; high mobility group AT-hook protein 1; high mobility group HMGA1A; high mobility group HMGA1B; high mobility group protein; high mobility group protein 1A; high mobility group protein A1; high mobility group protein A1A; high mobility group protein A1B; high mobility group protein HMG-I/HMG-Y; high mobility group protein I; high mobility group protein R; high mobiliy group protein A1B; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1; Hmga1a; Hmga1b; Hmgi; HMG-I(Y); HMGIY; HMG-R; Hmgy; MGC12816; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; non-histone protein; non-histone protein; HMGA1A; non-histone protein; HMGA1B; OTTHUMP00000016222; OTTHUMP00000016223; OTTHUMP00000016224; OTTHUMP00000039618
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3159
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P17096
• Gene Symbols: HMGA1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGA1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG