Invitrogen™ HMGB2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5120546	100 μL

Catalog No. PIPA5120546 Supplier Invitrogen™ Supplier No. PA5120546

Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, 293T, U-87MG, RAW264.7, PC-12. The target is usually found in the following locations: Chromosome, Cytoplasm, Nucleus, Secreted. Immunogen sequence: SAFFLFCSEH RPKIKSEHPG LSIGDTAKKL GEMWSEQSAK DKQPYEQKAA KLKEKYEKDI AAYRAKGKSE AGKKGPGRPT GSKKKNEPED EEEEEEEEDE D.

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Specifications

• Antigen: HMGB2
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 2.66 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene: Hmgb2
• Gene Accession No.: P26583, P30681, P52925
• Gene Alias: C80539; high mobility group box 2; high mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 2; HMG 2; HMG B2; Hmg2; HMG-2; HMGB2; HMG-B2; HMGB-2
• Gene Symbols: Hmgb2
• Host Species: Rabbit
• Immunogen: Synthetic peptide.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29395, 3148, 97165
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG