Invitrogen™ HMGCL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530059

Catalog No. PIPA530059

Description

Recommended positive controls: A549, HeLa. Predicted reactivity: Mouse (85%), Rat (86%), Chicken (80%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HMGCL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMGCL
• Gene Alias: 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; AW476067; HL; Hmgcl; HMG-CoA lyase; hydroxymethylglutaricaciduria; hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3155
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.44 mg/mL
• Formulation: 0.1M Tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P35914
• Gene Symbols: HMGCL
• Immunogen: Recombinant fragment corresponding to a region within amino acids 69 and 290 of Human HMGCL.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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