Invitrogen™ HMGCS2 Recombinant Rabbit Monoclonal Antibody (5T5T3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537869

Catalog No. PIMA537869

Description

Positive Samples: HepG2, Mouse liver, Rat liver Immunogen sequence: AFSYGSGLAA SFFSFRVSQD AAPGSPLDKL VSSTSDLPKR LASRKCVSPE EFTEIMNQRE QFYHKVNFSP PGDTNSLFPG TWYLERVDEQ HRRKYARRPV.

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HMGCS2
• Classification: Recombinant Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P22791, P54868, P54869
• Gene Symbols: HMGCS2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 409-508 of human HMGCS2 (P54868).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5T5T3
• Conjugate: Unconjugated
• Gene: HMGCS2
• Gene Alias: 1300002P16; 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-coenzyme A synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); hmgCoA; HMG-CoA synthase; Hmgcs1; Hmgcs2; hydroxymethylglutaryl-CoA synthase 2; hydroxymethylglutaryl-CoA synthase, mitochondrial; mHS; Mt3h3mg; testicular tissue protein Li 88
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15360, 24450, 3158
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov