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Invitrogen™ HMOX1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA588074
Description
Immunogen sequence: MERPQPDSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQA; Positive Samples: A-549, Mouse kidney, Mouse spleen, Rat kidney; Cellular Location: Cytoplasmic side, Endoplasmic reticulum membrane, Microsome, Peripheral membrane protein.
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
Specifications
HMOX1 | |
Polyclonal | |
Unconjugated | |
HMOX1 | |
bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein | |
Rabbit | |
Affinity chromatography | |
RUO | |
15368, 24451, 3162 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
0.92 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
P06762, P09601, P14901 | |
HMOX1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_0021241). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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