HNF1A Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS1405R

Catalog No. 50-198-3184

Description

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Specifications

• Antigen: HNF1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hnf1a
• Gene Alias: AI323641; albumin proximal factor; hepatic nuclear factor 1; hepatic nuclear factor-1-alpha; hepatocyte nuclear factor 1; Hepatocyte nuclear factor 1-alpha; HNF1; Hnf-1; HNF1 homeobox A; HNF1[a]; Hnf1a; Hnf-1a; Hnf1alpha; HNF-1-alpha; HNF1-alpha; IDDM20; interferon production regulator factor; LFB1; LF-B1; LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1; LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1; Liver-specific transcription factor LF-B1; MODY3; Tcf1; TCF-1; Transcription factor 1; Transcription factor 1 hepatic; transcription factor 1, hepatic
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6927
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P20823
• Gene Symbols: Hnf1a
• Immunogen: KLH conjugated synthetic peptide derived from rat HNF1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG