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HNF1A Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983184
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100 μL
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50-198-3184 100 μL
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Catalog No. 50-198-3184 Supplier Bioss Supplier No. BS1405R
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Rabbit Polyclonal Antibody

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Specifications

Antigen HNF1A
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Hnf1a
Gene Accession No. P20823
Gene Alias AI323641; albumin proximal factor; hepatic nuclear factor 1; hepatic nuclear factor-1-alpha; hepatocyte nuclear factor 1; Hepatocyte nuclear factor 1-alpha; HNF1; Hnf-1; HNF1 homeobox A; HNF1[a]; Hnf1a; Hnf-1a; Hnf1alpha; HNF-1-alpha; HNF1-alpha; IDDM20; interferon production regulator factor; LFB1; LF-B1; LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1; LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1; Liver-specific transcription factor LF-B1; MODY3; Tcf1; TCF-1; Transcription factor 1; Transcription factor 1 hepatic; transcription factor 1, hepatic
Gene Symbols Hnf1a
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from rat HNF1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6927
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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