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HNF1B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728046 Shop All Proteintech Group Inc Products
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50-172-8046 150 μL
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Catalog No. 50-172-8046 Supplier Proteintech Group Inc Supplier No. 125331AP150UL
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Rabbit Polyclonal Antibody

This is a rabbit polyclonal antibody raised against the N-terminal region of human HNF1B. HNF1B exists some isoforms with MW of 61 kDa, 58 kDa, 46 kDa, and 44 kDa.

Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors. It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas. Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen HNF1B
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene HNF1B
Gene Accession No. P23899, P27889, P35680
Gene Alias FJHN, HNF 1 beta, HNF 1B, HNF1 homeobox B, HNF1B, HNF1beta, HNF2, Homeoprotein LFB3, HPC11, LF B3, LFB3, MODY5, TCF 2, TCF2, Transcription factor 2, VHNF1
Gene Symbols Hnf1b
Host Species Rabbit
Immunogen HNF1B Fusion Protein Ag3232
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21410, 25640, 6928
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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