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Invitrogen™ HNF6 Polyclonal Antibody
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Catalog No. PIPA551938
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100 μL
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PIPA551938 100 μL
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Catalog No. PIPA551938 Supplier Invitrogen™ Supplier No. PA551938
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SMNNLYTPYH KDVAGMGQSL SPLSSSGLGS IHNSQQGLPH YAHPGAAMPT DKMLTPNGFE AHHPAMLGRH GEQHLTPTSA GMVPINGLPP HHPHAHLNAQ GHGQLLGTAR EPNPSVTGAQ VSNGSNSGQM EEINTKEV Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HNF6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ONECUT1
Gene Accession No. Q9UBC0
Gene Alias D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6a; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450
Gene Symbols ONECUT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HNF6. Recombinant protein control fragment (Product #RP-100744).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3175
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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