Invitrogen™ HNF6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579770

Catalog No. PIPA579770

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human HUH7 whole cell, rat liver tissue, rat RH35 whole cell, mouse liver tissue .

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Specifications

• Antigen: HNF6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ONECUT1
• Gene Alias: D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6a; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15379, 25231, 3175
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.01mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: O08755, P70512, Q9UBC0
• Gene Symbols: ONECUT1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HNF6 (187-203aa LGSIHNSQQGLPHYAHP).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG