Invitrogen™ HNF6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588749

Catalog No. PIPA588749

Description

Immunogen sequence: PYHKDVAGMG QSLSPLSSSG LGSIHNSQQG LPHYAHPGAA MPTDKMLTPN GFEAHHPAML GRHGEQHLTP TSAGMVPING LPPHHPHAHL NAQGHGQLLG TAREPNPSVT GAQVSNGSNS GQMEEI; Positive Samples: Jurkat, Mouse brain, Mouse spleen, Mouse testis, Rat brain; Cellular Location: Nucleus.

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Specifications

• Antigen: HNF6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ONECUT1
• Gene Alias: D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6a; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15379, 25231, 3175
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.6 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O08755, P70512, Q9UBC0
• Gene Symbols: ONECUT1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human ONECUT1 (NP_0044891).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG