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Invitrogen™ HNMT Polyclonal Antibody
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Catalog No. PIPA5102623
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100 μL
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PIPA5102623 100 μL
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Catalog No. PIPA5102623 Supplier Invitrogen™ Supplier No. PA5102623
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HNMT.

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HNMT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Hnmt
Gene Accession No. P50135, Q01984, Q91VF2
Gene Alias 1500031F01Rik; AI788969; histamine N-methyltransferase; Hmt; Hnmt; HNMT-S1; HNMT-S2; MRT51
Gene Symbols Hnmt
Host Species Rabbit
Immunogen A synthesized peptide derived from human HNMT(Accession P50135), corresponding to amino acid residues L211-E261.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140483, 3176, 81676
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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