Invitrogen™ hnRNP AB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113701

Catalog No. PIPA5113701

Description

Immunogen sequence: GAAAGAGGAT AAPPSGNQNG AEGDQINASK NEEDAGKMFV GGLSWDTSKK For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 86%; Dog: 86%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 93%.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: hnRNP AB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPAB
• Gene Alias: 3010025C11Rik; A1F-C1; ABBP1; ABBP-1; apobec-1 binding protein 1; APOBEC1-binding protein 1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1; CArG-binding factor-A; Cbf-a; Cgbfa; Heterogeneous nuclear ribonucleoprotein A/B; hnRNP A/B; hnRNP type A/B protein; HNRNPAB; Hnrpab; S1 protein D2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3182
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99729
• Gene Symbols: HNRNPAB
• Immunogen: Synthetic peptide directed towards the N terminal region of human HNRPAB (aa 34-83).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov