Invitrogen™ hnRNP C Polyclonal Antibody

Catalog No.	Quantity
PIPA5120666	100 μL

Catalog No. PIPA5120666 Supplier Invitrogen™ Supplier No. PA5120666

Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, U-251MG, K-562, Rat testis. The target is usually found in the following locations: Nucleus. Immunogen sequence: AEPKVNRGKA GVKRSAAEMY GSVTEHPSPS PLLSSSFDLD YDFQRDYYDR MYSYPARVPP PPPIARAVVP SKRQRVSGNT SRRGKSGFNS KSGQRGSSKS GKLKG.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

Specifications

• Antigen: hnRNP C
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.82 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene: HNRNPC
• Gene Accession No.: G3V9R8, P07910, Q9Z204
• Gene Alias: AL022939; C1; C2; D14Wsu171e; heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous ribonucleoprotein C1/C2; HNRNP; hnRNP C; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; Hnrnpc; hnrnp-C; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122; SNRPC
• Gene Symbols: HNRNPC
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 86-190 of human hnRNP C (NP_112604.2).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 15381, 290046, 3183
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG