Invitrogen™ hnRNP C1/C2 Monoclonal Antibody (4F4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA124631

Catalog No. PIMA124631

Description

Recommended positive controls: HeLa nuclear extract. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.

Specifications

• Antigen: hnRNP C1/C2
• Classification: Monoclonal
• Concentration: 2.4 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P07910
• Gene Symbols: HNRNPC
• Immunogen: RNP's eluted from oligo (dT) cellulose column.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Hamster, Chicken
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot, RNA Immunoprecipitation, Immunocytochemistry, Western Blot
• Clone: 4F4
• Conjugate: Unconjugated
• Gene: HNRNPC
• Gene Alias: AL022939; bZ1G18.4; C1; C2; D14Wsu171e; fb57h12; fi16b11; heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoprotein C; heterogeneous ribonucleoprotein C1/C2; HNRNP; hnRNP C; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; HNRNPC; hnrnp-C; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; hypothetical protein LOC406352; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122; SNRPC; wu:fb57h12; wu:fi16b11; zgc:55701
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100751290, 3183
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid