Invitrogen™ hnRNP DL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588026

Catalog No. PIPA588026

Description

Immunogen sequence: NIELPMDTKT NERRGFCFIT YTDEEPVKKL LESRYHQIGS GKCEIKVAQP KEVYRQQQQQ QKGGRGAAAG GRGGTRGRGR GQGQNWNQGF NNYYDQGYGN YNSAYGGDQN YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY; Positive Samples: Jurkat, SW620, HepG2, Mouse brain, Mouse testis, Rat brain; Cellular Location: Cytoplasm, Nucleus.

hnRNP DL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

Specifications

• Antigen: hnRNP DL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPDL
• Gene Alias: A+U-rich element RNA binding factor; AA407431; AA959857; AU-rich element RNA-binding factor; D5Ertd650e; D5Wsu145e; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); heterogeneous nuclear ribonucleoprotein D like; heterogeneous nuclear ribonucleoprotein D-like; heterogenous ribonucleoprotein D-like; HNRNP; hnRNP DL; hnRNP D-like; HNRNPD; Hnrnpdl; hnRNP-DL; Hnrnpdl1; HNRPDL; hnRPD-like protein; JKT41-binding protein; JKTBP; JKTBP2; laAUF1; LGMD1G; LOC534770 protein; protein laAUF1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 305178, 50926, 9987
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14979, Q3SWU3, Q9Z130
• Gene Symbols: HNRNPDL
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 261-420 of human HNRNPDL (NP_1127401).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG