Invitrogen™ hnRNP F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579382

Catalog No. PIPA579382

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human SKOV3 whole cell, human 293T whole cell, human Hela whole cell, human PANC-1 whole cell, human RT4 whole cell, human K562 whole cell, human U20S whole cell, human PC-3 whole cell, rat liver tissue, rat RH35 whole cell, rat C6 whole cell, mouse liver tissue, mouse SP2/0 whole cell, mouse HEPA1-6 whole cell. IHC: human mammary cancer tissue, human intestinal cancer tissue, mouse intestine tissue, rat intestine tissue. ICC/IF: SKOV-3 cell. Flow: U87 cell.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins. The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: hnRNP F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hnrnpf
• Gene Alias: 4833420I20Rik; AA407306; heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; hnRNP F; HnRNP F protein; hnRNP H; Hnrnpf; HNRNPH1; Hnrpf; mcs94 1; mcs94-1; Nucleolin-like protein mcs94-1; OK/SW-cl.23; ribonucleoprotein F; ROF
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3185, 64200, 98758
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P52597, Q794E4, Q9Z2X1
• Gene Symbols: Hnrnpf
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HnRNP F (23-53aa SVEDVQNFLSDCTIHDGAAGVHFIYTREGRQ).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov