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Invitrogen™ hnRNP H2 Polyclonal Antibody

Catalog No. PIPA535895
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100 μL
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PIPA535895 100 μL
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Catalog No. PIPA535895 Supplier Invitrogen™ Supplier No. PA535895
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Rat heart, Mouse heart. Predicted reactivity: Mouse (100%), Rat (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq].
TRUSTED_SUSTAINABILITY

Specifications

Antigen hnRNP H2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene HNRNPH2
Gene Accession No. P55795, P70333, Q6AY09
Gene Alias DXHXS1271E; Ftp3; Ftp-3; H'; Heterogeneous nuclear ribonucleoprotein H'; heterogeneous nuclear ribonucleoprotein H2; heterogeneous nuclear ribonucleoprotein H2 (H'); Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed; heterogeneous nuclear ribonucleoprotein H-prime; HNRNP; hnRNP H'; hnRNP H2; hnRNPH'; Hnrnph2; HNRPH'; HNRPH2
Gene Symbols HNRNPH2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human hnRNP H2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 308650, 3188, 56258
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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