Invitrogen™ hnRNP H3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100558

Catalog No. PIPA5100558

Description

Antibody detects endogenous levels of total HNRNPH3.

HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.

Specifications

• Antigen: hnRNP H3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPH3
• Gene Alias: 2H9; AA693301; AI666703; heterogeneous nuclear ribonucleoprotein 2H9; Heterogeneous nuclear ribonucleoprotein H3; heterogeneous nuclear ribonucleoprotein H3 (2H9); hnRNP 2H9; hnRNP H3; HNRNPH3; HNRPH3; Unknown (protein for MGC:136953); zgc:136953
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3189, 361838, 432467
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P31942
• Gene Symbols: HNRNPH3
• Immunogen: A synthesized peptide derived from human HNRNPH3(Accession P31942), corresponding to amino acid residues G284-Q334.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov