Invitrogen™ hnRNP K Monoclonal Antibody (3C2)

Catalog No.	Quantity
PIMA536291	50 μL

Catalog No. PIMA536291 Supplier Invitrogen™ Supplier No. MA536291

Description

Mouse Monoclonal Antibody

Western blot detects a band of approximately 65 kDa (predicted molecular weight: 51 kDa).

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Specifications

• Antigen: hnRNP K
• Applications: ChIP Assay, ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 3C2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: HNRNPK
• Gene Accession No.: P61978, P61979, P61980, Q3T0D0
• Gene Alias: AUKS; CSBP; dC stretch-binding protein; dC-stretch binding protein; FLJ41122; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K S homeolog; hnRNP K; Hnrnpk; hnRNP-K protein; hnrnpk.S; hnrpk; KBBP; NOVA; RP11-575L7.1; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNP; XELAEV_18010151mg
• Gene Symbols: HNRNPK, hnrnpk.S
• Host Species: Mouse
• Immunogen: Full length native protein (purified) (Human).
• Purification Method: Protein A
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100762670, 117282, 15387, 3190, 380255, 528135
• Target Species: Human, Mouse, Rat, Bovine, Hamster, Frog
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b