Invitrogen™ hnRNP K Recombinant Rabbit Monoclonal Antibody (3O5Y4)

Catalog No.	Quantity
PIMA535058	100 μL

Catalog No. PIMA535058 Supplier Invitrogen™ Supplier No. MA535058

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: METEQPEETF PNTETNGEFG KRPAEDMEEE QAFKRSRNTD EMVELRILLQ SKNAGAVIGK GGKNIKALRT DYNASVSVPD SSGPERILSI SADIETIGEI.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Specifications

• Antigen: hnRNP K
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 3O5Y4
• Concentration: 0.6 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: HNRNPK
• Gene Accession No.: P61978, P61979, P61980
• Gene Alias: AUKS; CSBP; dC stretch-binding protein; dC-stretch binding protein; FLJ41122; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K S homeolog; hnRNP K; Hnrnpk; hnRNP-K protein; hnrnpk.S; hnrpk; KBBP; NOVA; RP11-575L7.1; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNP; XELAEV_18010151mg
• Gene Symbols: HNRNPK
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human hnRNP K (P61978).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117282, 15387, 3190
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG