Invitrogen™ hnRNP K Recombinant Rabbit Monoclonal Antibody (SC60-03)

Catalog No.	Quantity
PIMA532210	100 μL

Catalog No. PIMA532210 Supplier Invitrogen™ Supplier No. MA532210

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Specifications

• Antigen: hnRNP K
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Recombinant Monoclonal
• Clone: SC60-03
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene: HNRNPK
• Gene Accession No.: P61978, P61979, P61980
• Gene Alias: AUKS; CSBP; dC stretch-binding protein; dC-stretch binding protein; FLJ41122; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K S homeolog; hnRNP K; Hnrnpk; hnRNP-K protein; hnrnpk.S; hnrpk; KBBP; NOVA; RP11-575L7.1; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNP; XELAEV_18010151mg
• Gene Symbols: HNRNPK
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human hnRNP K aa 1-49.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117282, 15387, 3190
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG