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Invitrogen™ hnRNP L Monoclonal Antibody (4D11)
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Catalog No. PIMA546550
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50 μg
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Catalog No. Quantity
PIMA546550 50 μg
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Catalog No. PIMA546550 Supplier Invitrogen™ Supplier No. MA546550
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Description

Mouse Monoclonal Antibody

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Western blot detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen hnRNP L
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4D11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene HNRNPL
Gene Accession No. F1LQ48, P14866, Q8R081
Gene Alias C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
Gene Symbols HNRNPL
Host Species Mouse
Immunogen Human hnRNP proteins, from HeLa cells, purified by affinity chromatography on ssDNA agarose.
Purification Method Protein A
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15388, 3191, 80846
Target Species Human, Mouse, Rat, Amphibian
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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