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Invitrogen™ hnRNP L Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5113689
Description
Immunogen sequence: AAGGGGGGEN YDDPHKTPAS PVVHIRGLID GVVEADLVEA LQEFGPISYV For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.
Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Specifications
hnRNP L | |
Polyclonal | |
Unconjugated | |
HNRNPL | |
C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14 | |
Rabbit | |
Affinity chromatography | |
RUO | |
15388, 3191 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
P14866, Q8R081 | |
HNRNPL | |
Synthetic peptide directed towards the N terminal region of human HNRPL (aa 82-131). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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