Invitrogen™ hnRNP M Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530247

Catalog No. PIPA530247

Description

Recommended positive controls: 293T, HeLa. Predicted reactivity: Mouse (97%), Rat (98%), Chicken (91%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: hnRNP M
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPM
• Gene Alias: 2610023M21Rik; AA409009; CEA receptor; CEAR; heterogeneous nuclear ribonucleoprotein M; heterogenous nuclear ribonucleoprotein M4; hnRNA-binding protein M4; hnRNP M; HNRNPM; HNRNPM4; Hnrpm; Hnrpm4; HTGR1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M; M4 protein; mKIAA4193; N-acetylglucosamine receptor 1; NAGR1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4670
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P52272
• Gene Symbols: HNRNPM
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 220 of Human HNRNPM.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov