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Invitrogen™ hnRNP M1-M4 Polyclonal Antibody
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Catalog No. PIPA599438
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100 μL
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PIPA599438 100 μL
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Catalog No. PIPA599438 Supplier Invitrogen™ Supplier No. PA599438
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total hnRNP M.

Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3'-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.
TRUSTED_SUSTAINABILITY

Specifications

Antigen hnRNP M1-M4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HNRNPM
Gene Accession No. P52272, Q62826, Q9D0E1
Gene Alias 2610023M21Rik; AA409009; CEA receptor; CEAR; Heterogeneous nuclear ribonucleoprotein M; heterogenous nuclear ribonucleoprotein M4; hnRNA-binding protein M4; hnRNP M; HNRNP3; Hnrnpm; HNRNPM3; HNRNPM4; HNRPM; Hnrpm4; HTGR1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M; M4 protein; mKIAA4193; N-acetylglucosamine receptor 1; NAGR1
Gene Symbols HNRNPM
Host Species Rabbit
Immunogen A synthesized peptide derived from human HNRNPM(Accession P52272), corresponding to amino acid residues G23-A73.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116655, 4670, 76936
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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