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hnRNP M3/4 Mouse anti-Human, Mouse, Clone: 2A6-2H3, Bethyl Laboratories

Catalog No. 501571232
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50-157-1232 20 μL
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Catalog No. 50-157-1232 Supplier Bethyl Laboratories, Inc Supplier No. A500011AT
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Description

Mouse Monoclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3′-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.

Specifications

Antigen hnRNP M3/4
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 2A6-2H3
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene HNRNPM
Gene Accession No. P52272, Q9D0E1
Gene Alias heterogeneous nuclear ribonucleoprotein M, HNRNPM, HNRNPM4, HNRPM, hnRNA-binding protein M4, HNRNPM3, hnRNA-binding protein M3, HNRNP3, N-acetylglucosamine receptor 1, M4 protein
Gene Symbols HNRNPM
Host Species Mouse
Immunogen hnRNP M1-4 proteins
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4670, 76936
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b
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