HNRNPL Mouse anti-Human, Clone: OTI2E4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF805417

Catalog No. 50-166-7421

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Heterogeneous nuclear RNAs which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HNRNPL
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: HNRNPL
• Gene Alias: HNRPL, P/OKcl.14, hnRNP-L
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3191
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2E4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P14866
• Gene Symbols: HNRNPL
• Immunogen: Human recombit protein fragment corresponding to amino acids 270-502 of human HNRNPL produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1