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Invitrogen™ HO-1 Monoclonal Antibody (1F12-A6), FITC
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA545153
This item is not returnable.
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Description
1 μg/mL was sufficient for detection of HO-1 in 10 μg of mixed human cell line lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary. Detects 32kDa. Does not cross-react with HO-2.
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
Specifications
HO-1 | |
Monoclonal | |
1 mg/mL | |
PBS, 9.09mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.2 | |
P06762, P09601, P14901, P32394, Q5E9F2 | |
HMOX1 | |
Human HO-1 synthetic peptide, amino acids 1-30. | |
100 μg | |
Primary | |
Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Hamster, Pig, Guinea Pig | |
Antibody | |
IgG1 κ |
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
1F12-A6 | |
FITC | |
HMOX1 | |
bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein | |
Mouse | |
Protein G | |
RUO | |
100008919, 100715748, 100756872, 15368, 24451, 3162, 442987, 445512, 513221 | |
4°C, store in dark | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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