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Invitrogen™ HO-1 Monoclonal Antibody (6B8-2F2), PerCP
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Catalog No. PIMA545348
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100 μg
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Catalog No. Quantity
PIMA545348 100 μg
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Catalog No. PIMA545348 Supplier Invitrogen™ Supplier No. MA545348
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45348 was sufficient for detection of HO-1 in 10 μg of rat kidney lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 32kDa. Does not cross-react with HO-2.

Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HO-1
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6B8-2F2
Concentration 1 mg/mL
Conjugate PerCP
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative
Gene HMOX1
Gene Accession No. P06762, P09601, P14901
Gene Alias bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein
Gene Symbols HMOX1
Host Species Mouse
Immunogen His-tagged Rat HO-1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15368, 24451, 3162
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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