Invitrogen™ HOMER3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579384

Catalog No. PIPA579384

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human PC-3 whole cell, human U251 whole cell, human A431 whole cell, rat brain tissue, rat lung tissuemouse brain tissuemouse lung tissue. IHC: human mammary cancer tissue, human intestinal cancer tissue, human lung cancer tissue.

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: HOMER3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOMER3
• Gene Alias: AW146114; homer homolog 3; homer homolog 3 (Drosophila); homer protein homolog 3; homer scaffolding protein 3; Homer, neuronal immediate early gene, 3; HOMER3; homer-3; VASP/Ena-related gene up-regulated during seizure and LTP 3; Vesl3; Vesl-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26558, 29548, 9454
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q99JP6, Q9NSC5, Q9Z2X5
• Gene Symbols: HOMER3
• Immunogen: E. coli-derived human HOMER3 recombinant protein (Position: R282-A360).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov